Ans. Yes it possible to map and share a network drive to your VPS, then you can drag and drop files across to your hosted webspace without having to use FTP.

If your are using the Plesk control panel in your VPS, samba can be configured using the supplied Plesk module. However we would recommend creating a VPN first, and then configure samba to only listen on the VPN network interface  (typically tap0) as a security measure.